Evaluating soil nitrate dynamics in an intercropping dripped ecosystem using HYDRUS-2D.

The competition mechanisms between crop species for water and nutrients, especially nitrate (NO3-N), in intercropping ecosystems are still poorly understood. Therefore, an experiment involving high (300 kg ha-1 for corn and 250 kg ha-1 for tomato), medium (210 kg ha-1 for corn and 175 kg ha-1 for tomato), and low (150 kg ha-1 for corn and 125 kg ha-1 for tomato) N-fertilizer applications (HF, MF, LF, respectively) was conducted in the corn and tomato intercropping ecosystem during 2014 (a calibration period for modeling) and 2015 (a validation period for modeling). The modified HYDRUS-2D code was used to analyze soil NO3-N concentrations (SNC) in the middle between corn rows (Pc), between corn and tomato rows (Pb), and between tomato rows (Pt), NO3-N exchange in the horizontal direction between different regions, NO3-N leaching from the corn, the bare, and the tomato region, and N uptake by crops. Simulated SNCs were in good agreement with measurements, with RMSE, NSE, and MRE of 0.01-0.06 mg cm-3, 0.75-0.98, and 8.7-19.1%, respectively, during the validation period (2015). Average SNCs in the 0-40 cm soil layer were different between Pc, Pt, and Pb. Intensive NO3-N exchange in the horizontal direction occurred during the second stage (Day After Sowing [DAS] 37-113 in 2014; DAS 29-120 in 2015). NO3-N exchange between the corn and bare regions was lower than between the tomato and bare regions due to smaller concentration gradients. However, in the vertical direction, NO3-N leaching from the corn region in both years was 4.1 and 8.8 times larger, respectively, than from the tomato region under HF since NO3-N mainly moved from the tomato region to the corn region. Our results reveal the competition between corn and tomato for N and provide a rationale for formulating and optimizing different fertilizer regimes for different crops in the intercropping ecosystem

Dissipative elastic metamaterial with a lowfrequency passband

We design and experimentally demonstrate a dissipative elastic metamaterial structure that functions as a bandpass filter with a low-frequency passband. The mechanism of dissipation in this structure is well described by a mass-spring-damper model that reveals that the imaginary part of the wavenumber is non-zero, even in the passband of dissipative metamaterials. This indicates that transmittance in this range can be low. A prototype for this viscoelastic metamaterial model is fabricated by 3D printing techniques using soft and hard acrylics as constituent materials. The transmittance of the printed metamaterial is measured and shows good agreement with theoretical predictions, demonstrating its potential in the design of compact waveguides, filters and other advanced devices for controlling mechanical waves

Dissipative elastic metamaterial with a lowfrequency passband

We design and experimentally demonstrate a dissipative elastic metamaterial structure that functions as a bandpass filter with a low-frequency passband. The mechanism of dissipation in this structure is well described by a mass-spring-damper model that reveals that the imaginary part of the wavenumber is non-zero, even in the passband of dissipative metamaterials. This indicates that transmittance in this range can be low. A prototype for this viscoelastic metamaterial model is fabricated by 3D printing techniques using soft and hard acrylics as constituent materials. The transmittance of the printed metamaterial is measured and shows good agreement with theoretical predictions, demonstrating its potential in the design of compact waveguides, filters and other advanced devices for controlling mechanical waves

Molecular and clinical characteristics of ATP1A3-related diseases

ObjectiveWith detailed studies of ATP1A3-related diseases, the phenotypic spectrum of ATP1A3 has greatly expanded. This study aimed to potentially identify the mechanisms by which ATP1A3 caused neurological dysfunction by analyzing the clinical features and phenotypes of ATP1A3-related diseases, and exploring the distribution patterns of mutations in the subregions of the ATP1A3 protein, thus providing new and effective therapeutic approaches.MethodsDatabases of PubMed, Online Mendelian Inheritance in Man, and Human Gene Mutation Database, Wanfang Data, and Embase were searched for case reports of ATP1A3-related diseases. Following case screening, we collected clinical information and genetic testing results of patients, and analyzed the disease characteristics on the clinical phenotype spectrum associated with mutations, genetic characteristics of mutations, and effects of drug therapy.ResultsWe collected 902 clinical cases related to ATP1A3 gene. From the results of previous studies, we further clarified the clinical characteristics of ATP1A3-related diseases, such as alternating hemiplegia of childhood (AHC), rapid-onset dystonia-parkinsonism; cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss syndrome, and relapsing encephalopathy with cerebellar ataxia, frequency of mutations in different phenotypes and their distribution in gene and protein structures, and differences in mutations in different clinical phenotypes. Regarding the efficacy of drug treatment, 80 of the 124 patients with AHC were treated with flunarizine, with an effectiveness rate of ~64.5%.ConclusionsNervous system dysfunction due to mutations of ATP1A3 gene was characterized by a group of genotypic–phenotypic interrelated disease pedigrees with multiple clinical manifestations. The presented results might help guide the diagnosis and treatment of ATP1A3-related diseases and provided new ideas for further exploring the mechanisms of nervous system diseases due to ATP1A3 mutations